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  5. Tocris Bioscience™ SCH 336

Tocris Bioscience™ SCH 336
GREENER_CHOICE

Catalog No. 581510
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly potent and selective CB2 inverse agonist

SCH 336 is a highly potent and selective CB2 receptor inverse agonist (Ki = 1.8 nM, EC50 = 2 nM). Displays 100-fold selectivity for CB2 receptors over CB1. Increases forskolin stimulated cAMP accumulation in CHO cells expressing human CB2 receptors. Inhibits leukocyte migration in a murine model of delayed-type hypersensitivity and inhibits antigen-induced lung eosinophilia in a mouse allergy model.

Specifications

Chemical Name or Material N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide
CAS 447459-51-0
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C23H25NO8S3
Formula Weight Observed MW: 539.64
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