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  6. 555310

Tocris Bioscience™ Sephin 1

Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1

Supplier:  Tocris Bioscience™ 5553/10

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Catalog No. 555310


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Description

Description

Sephin 1 is an inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1. Does not bind PPP1R15B or have α2 adrenergic agonist activity. Cytoprotective in endoplasmic reticulum stressed cells in vitro. Prevents defects associated with protein misfolding in a mouse Charcot-Marie Tooth-1B model. Orally available.
Specifications

Specifications

(2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Protein Ser/Thr Phosphatase Inhibitors
258.66
10 mg
C8H9ClN4.CH2O3
>98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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