DescriptionInhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1. Does not bind PPP1R15B or have α2 adrenergic agonist activity. Cytoprotective in endoplasmic reticulum stressed cells in vitro. Prevents defects associated with protein misfolding in a mouse Charcot-Marie Tooth-1B model. Orally available.
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|(2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt|
|Target: Protein Ser/Thr Phosphatase Inhibitors|
Safety and Handling
Recommended Storage : Store at −20°C
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