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SFRS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 203711AP150UL

Description
The antibody has no cross reaction to SFRS2B.
SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5′- and 3′-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5′- and 3′-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5′-AGSAGAGTA-3′ (S=C or G) or 5′-GTTCGAGTA-3′ and can bind to beta-globin mRNA and commit it to the splicing pathway.Specifications
SFRS2 | |
Polyclonal | |
Unconjugated | |
SRSF2 | |
PR264, Protein PR264, SC 35, SC35, SFRS2, SFRS2A, Splicing component, 35 kDa, Splicing factor SC35, SRp30b, SRSF2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
20382, 494445, 6427 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q01130, Q62093, Q6PDU1 | |
Srsf2 | |
Peptide | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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