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SFRS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 203711AP150UL

Encompass_Preferred

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Catalog No. 50-557-097


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Description

Description

The antibody has no cross reaction to SFRS2B.

SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5′- and 3′-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5′- and 3′-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5′-AGSAGAGTA-3′ (S=C or G) or 5′-GTTCGAGTA-3′ and can bind to beta-globin mRNA and commit it to the splicing pathway.
Specifications

Specifications

SFRS2
Polyclonal
Unconjugated
SRSF2
PR264, Protein PR264, SC 35, SC35, SFRS2, SFRS2A, Splicing component, 35 kDa, Splicing factor SC35, SRp30b, SRSF2
Rabbit
Antigen Affinity Chromatography
RUO
20382, 494445, 6427
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q01130, Q62093, Q6PDU1
Srsf2
Peptide
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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