Potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1µM). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.
Chemical Name: 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline
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