Tocris™ SGX 523

Selective and potent c-MET kinase inhibitor

Manufacturer: Tocris™ 5356/10

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Catalog No. 53-561-0

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For Research Use Only


    Description SGX 523
    Molecular Weight 359.41
    Purity >99
    Quantity 10mg
    Product Type SGX 523

    Potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1µM). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.

    • Chemical Name: 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline
    • Formula: C18H13N7S
    • CAS Number: 1022150-57-7
    • Solubility: Soluble to 20mM in DMSO
    • Purity: >99

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