F10 Sheep anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-333	1 mg

Catalog No. 89-114-333 Supplier Abnova Corporation Supplier No. PAB0670

Description

Sheep polyclonal antibody raised against native F10.

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]

Specifications

• Antigen: F10
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against native F10.
• Dilution: Western Blot (25 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol)
• Gene: F10
• Gene Alias: FX/FXA
• Gene Symbols: F10
• Host Species: Sheep
• Immunogen: Native purified Human F10.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2159
• Test Specificity: This antibody recognizes human factor X.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only