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  5. Tocris Bioscience™ SI-2 hydrochloride, >98%

Tocris Bioscience™ SI-2 hydrochloride, >98%
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Catalog No. 596410
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59-641-0 10 mg
59-645-0 50 mg
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Catalog No. 59-641-0 Supplier Tocris Bioscience™ Supplier No. 5964/10
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Description

Steroid receptor coactivator 3 (SRC-3) inhibitor

Potent steroid receptor coactivator 3 (SRC-3) inhibitor. Reduces SRC1, SRC2 and SRC3 levels in breast cancer cell lines. Inhibits cell growth (IC50 = 3.4 nM), induces apoptosis and attenuates migration of MDA-MB48 breast cancer cells in vitro. Inhibits tumor growth in a MDA-MB48 cell breast cancer mouse model. Orally available.

Chemical Identifiers

CAS 287403-39-8
Molecular Formula C17H22N2O5S2

Specifications

Quantity 10 mg
Solubility Soluble to 50mM in water and to 20mM in DMSO
Formula Weight 301.78
Purity >98%
Molecular Weight (g/mol) 398.492
Chemical Name or Material (3S)-4-[[4-(2-Butyn-1-yloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-3-thiomorpholinecarboxamide

Safety and Handling

Recommended Storage Store at +4°C
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