Siglec-1/CD169 Antibody (ED3), DyLight 405, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10065301V

Catalog No. NB10065301V

Description

Siglec-1/CD169 Monoclonal specifically detects Siglec-1/CD169 in Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

• Antigen: Siglec-1/CD169
• Classification: Monoclonal
• Conjugate: DyLight 405
• Gene Alias: CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: NB100-65301 recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: ED3
• Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Symbols: SIGLEC1
• Immunogen: Rat Spleen cell homogenate
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Immunology
• Gene ID (Entrez): 6614
• Target Species: Rat
• Form: Purified

For Research Use Only