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Siglec-1/CD169 Antibody (ED3), Janelia Fluor™ 549, Novus Biologicals™
SDP

Catalog No. NB065301549 Shop All R&D Systems Products
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NB065301549 0.1 mL
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Catalog No. NB065301549 Supplier Novus Biologicals Supplier No. NB10065301JF549
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Description

Mouse Monoclonal Antibody

Siglec-1/CD169 Monoclonal specifically detects Siglec-1/CD169 in Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

Antigen Siglec-1/CD169
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone ED3
Conjugate Janelia Fluor 549
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin
Gene Symbols SIGLEC1
Host Species Mouse
Immunogen Rat Spleen cell homogenate
Purification Method Protein A purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 6614
Test Specificity NB100-65301 recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
Target Species Rat
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG2a
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