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Siglec-2/CD22 Antibody (hL22 (Epratuzumab)) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP275188 Shop All R&D Systems Products
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0.2 mg
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NBP275188 0.2 mg
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Catalog No. NBP275188 Supplier Novus Biologicals Supplier No. NBP275188
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Description

Human Monoclonal Antibody

Siglec-2/CD22 Monoclonal specifically detects Siglec-2/CD22 in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunoprecipitation, Block/Neutralize.

Specifications

Antigen Siglec-2/CD22
Applications Flow Cytometry, Immunoprecipitation, Blocking Assay
Classification Monoclonal
Clone hL22 (Epratuzumab)
Conjugate Unconjugated
Dilution Flow Cytometry 1:10 - 1:1000, Immunoprecipitation 1:10 - 1:500, Block/Neutralize
Formulation PBS with 0.02% Proclin 300
Gene Alias B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, CD22 antigenMGC130020, CD22 molecule, sialic acid binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2, SIGLEC-2, SIGLEC2FLJ22814, T-cell surface antigen Leu-14
Gene Symbols CD22
Host Species Human
Immunogen This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Purification Method Protein A purified
Quantity 0.2 mg
Primary or Secondary Primary
Gene ID (Entrez) 933.0
Test Specificity This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Target Species Human, Cynomolgus Monkey, Rhesus Macaque
Content And Storage Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Form Purified
Isotype IgG1 κ
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