Siglec-2/CD22 Antibody (hL22 (Epratuzumab)) - Azide and BSA Free, Novus Biologicals™

Human Monoclonal Antibody

Supplier:  Novus Biologicals NBP275188

Catalog No. NBP275188

Description

Siglec-2/CD22 Monoclonal specifically detects Siglec-2/CD22 in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunoprecipitation, Block/Neutralize.

Specifications

• Antigen: Siglec-2/CD22
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% Proclin 300
• Gene Symbols: CD22
• Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
• Quantity: 0.2 mg
• Gene ID (Entrez): 933.0
• Target Species: Human, Cynomolgus Monkey, Rhesus Macaque
• Form: Purified

• Applications: Flow Cytometry, Immunoprecipitation, Blocking Assay
• Clone: hL22 (Epratuzumab)
• Dilution: Flow Cytometry 1:10 - 1:1000, Immunoprecipitation 1:10 - 1:500, Block/Neutralize
• Gene Alias: B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, CD22 antigenMGC130020, CD22 molecule, sialic acid binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2, SIGLEC-2, SIGLEC2FLJ22814, T-cell surface antigen Leu-14
• Host Species: Human
• Purification Method: Protein A purified
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
• Content And Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Isotype: IgG1 κ