Tocris™ SirReal 2

Selective inhibitor of SIRT2

Manufacturer: Tocris™ 5457/50

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Catalog No. 54-575-0

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    Specifications

    Description SirReal 2
    Molecular Weight 420.55
    Purity >98
    Quantity 50mg
    Product Type SirReal 2

    Selective SIRT2 inhibitor (IC50 = 140nM). Has minimal effect on SIRT1 and SIRT3-6. Increases α-tubulin acetylation levels in HeLa cells.

    • Chemical Name: 2-[(4,6-Dimethyl-2-pyrimidinyl)thio]-N-[5-(1-naphthalenylmethyl)-2-thiazolyl]acetamide
    • Formula: C22H20N4OS2
    • CAS Number: 709002-46-0
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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