SIRT6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8845	Proteintech Group Inc 135721AP150UL	150 μL

Description

This antibody is a rabbit polyclonal antibody raised against full length human SIRT6 antigen.

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.

Specifications

• Antigen: SIRT6
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P59941, Q8N6T7
• Gene ID (Entrez): 299638, 50721, 51548
• Immunogen: SIRT6 Fusion Protein Ag4469
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SIRT6

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: SIR2 like protein 6, SIR2L6, SIRT6
• Gene Symbols: SIRT6
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody