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  5. Tocris Bioscience™ SKF 89976A hydrochloride

Tocris Bioscience™ SKF 89976A hydrochloride
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Catalog No. 108110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent GAT-1 inhibitor; brain penetrant

A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo.

Chemical Identifiers

CAS 85375-15-1
Molecular Formula C22H26ClNO2

Specifications

Quantity 10 mg
Formula Weight 371.91
Purity >99%
Molecular Weight (g/mol) 371.905
Chemical Name or Material SKF 89976A hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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