Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris Bioscience™ SKF 89976A hydrochloride
GREENER_CHOICE

Catalog No. 108110
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent GAT-1 inhibitor; brain penetrant

A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo.

Chemical Identifiers

CAS 85375-15-1
Molecular Formula C22H26ClNO2

Specifications

Quantity 10 mg
Formula Weight 371.91
Purity >99%
Molecular Weight (g/mol) 371.905
Chemical Name or Material SKF 89976A hydrochloride
Recommended Storage Desiccate at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.