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SL 327, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
10mg
50mg
This item is not returnable. View return policy
305350-87-2
C16H12F3N3S
335.348
JLOXTZFYJNCPIS-FYWRMAATSA-N
mek1/2 inhibitor,z-3-amino-3-4-aminophenylthio-2-2-trifluoromethyl phenyl acrylonitrile,2z-3-amino-3-4-aminophenyl sulfanyl-2-2-trifluoromethyl phenyl prop-2-enenitrile,z-& e-alpha-amino-4-aminophenyl thio methylene-2-trifluoromethyl benzeneacetonitrile,d04wpa,alpha-amino-4-aminophenylthio methylene-2-trifluoromethyl phenylacetonitrile,sl hplc , mixture of e & z isomers, solid,3-amino-3-4-aminophenyl sulfanyl-2-2-trifluoromethyl phenyl acrylonitrile,3-amino-3-4-aminophenyl thio-2-2-trifluoromethyl phenyl-2-propenenitrile,alpha-amino 4-aminophenyl thio methylene-2-trifluoromethyl benzeneacetonitrile
9549284
(Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
This item is not returnable. View return policy
305350-87-2
C16H12F3N3S
335.348
JLOXTZFYJNCPIS-FYWRMAATSA-N
mek1/2 inhibitor,z-3-amino-3-4-aminophenylthio-2-2-trifluoromethyl phenyl acrylonitrile,2z-3-amino-3-4-aminophenyl sulfanyl-2-2-trifluoromethyl phenyl prop-2-enenitrile,z-& e-alpha-amino-4-aminophenyl thio methylene-2-trifluoromethyl benzeneacetonitrile,d04wpa,alpha-amino-4-aminophenylthio methylene-2-trifluoromethyl phenylacetonitrile,sl hplc , mixture of e & z isomers, solid,3-amino-3-4-aminophenyl sulfanyl-2-2-trifluoromethyl phenyl acrylonitrile,3-amino-3-4-aminophenyl thio-2-2-trifluoromethyl phenyl-2-propenenitrile,alpha-amino 4-aminophenyl thio methylene-2-trifluoromethyl benzeneacetonitrile
9549284
(Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F

Selective inhibitor of MEK1 and MEK2; brain penetrant

Selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain penetrant in vivo, blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration.

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Quantity 10mg
Formula Weight 335.35
Percent Purity >99%
Chemical Name or Material SL 327

Recommended Storage : Desiccate at +4°C