Invitrogen™ SLC2A13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5107263

Catalog No. PIPA5107263

Description

Sequence homology: Cow: 79%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Rat: 79%.

SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.

Specifications

• Antigen: SLC2A13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC2A13
• Gene Alias: 6530403A04; A630029G22Rik; AI505012; Gm308; h(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; Hmit; proton (H+) myo-inositol symporter; proton myo-inositol cotransporter; proton myo-inositol symporter; SLC2A13; solute carrier family 2 (facilitated glucose transporter), member 13; solute carrier family 2 member 13
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114134
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q96QE2
• Gene Symbols: SLC2A13
• Immunogen: Synthetic peptide directed towards the middle region of human SLC2A13 (aa 396-446).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG