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SMER 28, Tocris Bioscience™
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Catalog No. 429750
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Positive regulator of autophagy

Positive regulator of autophagy in a mechanism independent from the mTOR pathway. Increases autophagosome synthesis and enhances clearance of model autophagy substrates such as mutant huntingtin and A53T α-synuclein, associated with Huntington's and Parkinson's diseases, respectively. Promotes reprogramming of fibroblasts to neural stem-like cells in combination with other chemical reagents.

Chemical Identifiers

CAS 307538-42-7
Molecular Formula C11H10BrN3
Molecular Weight (g/mol) 264.13
MDL Number MFCD02166825
InChI Key BCPOLXUSCUFDGE-UHFFFAOYSA-N
PubChem CID 1560402
IUPAC Name 6-bromo-N-(prop-2-en-1-yl)quinazolin-4-amine
SMILES BrC1=CC2=C(NCC=C)N=CN=C2C=C1

Specifications

Quantity 50 mg
Synonym smer28, smer 28, n-allyl-6-bromoquinazolin-4-amine, 6-bromo-n-2-propenyl-4-quinazolinamine, 6-bromo-n-prop-2-en-1-yl quinazolin-4-amine, 3srb, cbmicro_021891, smer26, cambridge id 6164173, smer28 2
Formula Weight 264.12
Percent Purity >99%
Chemical Name or Material SMER 28

Safety and Handling

Recommended Storage Store at +4°C
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