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SMN1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7141141
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50-156-1173 20 μL
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Catalog No. 50-156-1173 Supplier Bethyl Laboratories, Inc Supplier No. A301863AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.

Specifications

Antigen SMN1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SMN1
Gene Accession No. Q16637
Gene Alias BCD541, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMN2, SMNT, T-BCD541, component of gems 1; gemin 1; gemin-1; survival motor neuron protein
Gene Symbols SMN1
Host Species Rabbit
Immunogen Between 244 and 294
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6606
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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