Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
SMRT / NCoR2 Monoclonal Antibody (5.1), Active Motif™
Mouse Monoclonal Antibody
$132.55 - $397.65
Specifications
| Antigen | SMRT / NCoR2 |
|---|---|
| Clone | 5.1 |
| Concentration | 1 mg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3146
|
Active Motif
61106 |
10 μg |
Each for $132.55
|
|
|||||
|
50-199-3145
|
Active Motif
61105 |
100 μg |
Each for $397.65
|
|
|||||
Description
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.Specifications
| SMRT / NCoR2 | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
| CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; Nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; Silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; Smrt; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1 | |
| NCOR2 | |
| IgG1 | |
| Protein G | |
| Antibody |
| 5.1 | |
| Western Blot | |
| Unconjugated | |
| Mouse | |
| Human | |
| Q9Y618 | |
| 9612 | |
| This SMRT / NCoR2 antibody was raised against a recombinant protein corresponding to amino acids 2004-2310 of human SMRT / NCoR2. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| NCOR2 |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title