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Tocris Bioscience™ SNS 032
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Catalog No. 407510
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40-751-0 10 mg
40-755-0 50 mg
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Catalog No. 40-751-0 Supplier Tocris Bioscience™ Supplier No. 4075/10
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Description

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

Cyclin dependent kinase (cdk) inhibitor (reported IC50 values are 0.004 - 0.048, 0.0045 - 0.05, 0.062 - 0.29, 0.2-0.48, 0.4 and 0.45 μM for cdk9, cdk2, cdk7, cdk1, cdk5 and cdk4, respectively). Displays no activity against 190 additional kinases (IC50 >1 μM). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis.

Chemical Identifiers

CAS 345627-80-7
Molecular Formula C17H24N4O2S2

Specifications

Quantity 10 mg
Formula Weight 380.53
Purity >99%
Molecular Weight (g/mol) 380.525
Chemical Name or Material SNS 032

Safety and Handling

Recommended Storage Store at -20°C
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