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Invitrogen™ SNX15 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA518149
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 gene.
Specifications
SNX15 | |
Polyclonal | |
Unconjugated | |
Snx15 | |
1500032B08Rik; clone iota unknown protein; E130013C21Rik; hCG_23393; HSAF001435; OTTHUMP00000035515; SNX15; sorting nexin 15; sorting nexin-15 | |
Goat | |
Ammonium Sulfate Precipitation | |
RUO | |
29907 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q9NRS6 | |
Snx15 | |
Synthetic peptide sequence (EEILRLHLSQLPP) corresponding to the C-terminus amino acids of SNX15 (aa 330-342). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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