Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ Sodium Channel Pan Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551019

Catalog No. PA551019


Only null left
Add to Cart

Description

Description

SCN1A Polyclonal Antibody detects endogenous levels of SCN1A protein.

Voltage-gated sodium channels (NaV) are essential for the generation of action potentials and for cell excitability. NaV channels are activated in response to depolarization and selectively allow flow of Na+ ions. To date, nine NaV alpha subunits have been cloned and named NaV1.1-NaV1.9. The NaV channels are classified into two groups according to their sensitivity to tetrodotoxin (TTX): TTX-sensitive (NaV1.1, NaV1.2, NaV1.3, NaV1.4, NaV1.6 and NaV1.7) and TTX-resistant (NaV1.5, NaV1.8 and NaV1.9). Mammalian sodium channels are heterotrimers, composed of a central, pore-forming alpha subunit and two auxiliary beta subunits. The expression of the alpha subunit isoform is developmentally regulated and tissue specific. Sodium channels in the adult central nervous system and heart contain beta 1 through beta 4 subunits, whereas sodium channels in adult skeletal muscle have only the beta 1 subunit.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Sodium Channel Pan
Polyclonal
Unconjugated
SCN1A
3-Feb; 6430408L10; A230052E19Rik; AI853486; alternative product; ataxia 3; B230332M13; BFIC3; BFIS3; BFNIS; brain III voltage-gated sodium channel; C630029C19Rik; cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; CDCD2; CERIII; CIAT; CMD1E; CMPD2; CMS16; CTC-264K15.6; dmu; EIEE11; EIEE13; EIEE6; ETHA; FEB3; FEB3A; FEB3B; FEPS2; FEPS3; FHM3; GEFSP2; GEFSP7; Gm1000; HB1; HB2; HBA; HBBD; HBSC II; HBSCI; HBSCII; HH1; hNa6/Scn8a voltage-gated sodium channel; hNaN; hNE-Na; HOKPP2; hPN3; HSAN2D; HSAN7; HYKPP; HYPP; ICCD; IVF; KIAA1356; Kiaa4197; LQT3; med; mH1; mH2; microI; mKIAA4197; mnd2; mnd-2; Mu-1; Na(v)1.2; Na(V)1.4; Na(V)1.8; Na+ channel; NAC1; NAC1A; NAC2; NAC3; naCh6; NachII; NaN; NaT; Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.5c; Nav1.6; Nav1.7; Nav1.8; NaV1.9; Nbna1; NCHVS; NENA; NE-NA; Neuroendocrine sodium channel; nmf2; nmf335; nmf58; NSS2; nur14; Peripheral nerve protein type 4; peripheral nerve sodium channel 3; Peripheral nerve sodium channel 5; peripheral sodium channel 1; PFHB1; PN1; PN3; PN4; PN5; RII/RIIA; RIIA sodium channel protein; RNSCPIIR; SCAL; SCIII; SCN; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; SCN2A; SCN2A1; SCN2A2; SCN3A; SCN4A; Scn5a; SCN8A; SCN9A; ScpII; seal; Sensory neuron sodium channel; sensory neuron sodium channel 2; SFNP; skeletal muscle sodium channel alpha subunit; skeletal muscle voltage-dependent sodium channel type IV alpha subunit; skM1; SkM2; SMEI; SNS; Sns2; SNS-2; sodium channel 25; sodium channel 6; sodium channel alpha-subunit; sodium channel protein brain I subunit alpha; Sodium channel protein brain II subunit alpha; sodium channel protein brain III subunit alpha; Sodium channel protein cardiac muscle subunit alpha; sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type 1 subunit alpha; sodium channel protein type 10 subunit alpha; Sodium channel protein type 11 subunit alpha; sodium channel protein type 2 subunit alpha; Sodium channel protein type 3 subunit alpha; sodium channel protein type 4 subunit alpha; Sodium channel protein type 5 subunit alpha; sodium channel protein type 8 subunit alpha; Sodium channel protein type 9 subunit alpha; sodium channel protein type I subunit alpha; Sodium channel protein type II subunit alpha; sodium channel protein type III subunit alpha; Sodium channel protein type IV subunit alpha; sodium channel protein type IX subunit alpha; Sodium channel protein type V subunit alpha; sodium channel protein type VIII subunit alpha; Sodium channel protein type X subunit alpha; sodium channel protein type XI subunit alpha; sodium channel protein, brain I alpha subunit; sodium channel protein, brain I subunit alpha; sodium channel protein, brain II subunit alpha; sodium channel protein, brain III subunit alpha; sodium channel protein, brain type 2 alpha subunit; sodium channel type X alpha polypeptide; sodium channel voltage gated type 1 alpha subunit; sodium channel voltage-gated type 11 alpha polypeptide; sodium channel voltage-gated type 4 alpha polypeptide; sodium channel voltage-gated type I alpha polypeptide; sodium channel voltage-gated type II alpha polypeptide; Sodium channel voltage-gated type IV alpha polypeptide; sodium channel voltage-gated type V alpha polypeptide; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel voltage-gated type XI alpha polypeptide; sodium channel, voltage gated, type I alpha subunit; sodium channel, voltage gated, type II alpha subunit; sodium channel, voltage gated, type III alpha subunit; sodium channel, voltage gated, type IV alpha subunit; sodium channel, voltage gated, type IX alpha subunit; sodium channel, voltage gated, type V alpha subunit; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage gated, type XI alpha subunit
Rabbit
Antigen affinity chromatography
RUO
110876, 110880, 11280, 20264, 20265, 20269, 20271, 20273, 20274, 24046, 24766, 25665, 25722, 29571, 29701, 29710, 497770, 6323, 6326, 6328, 6329, 6331, 6334, 6335, 6336, 78956, 81574
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
A2APX8, O08562, O88420, O88457, P04774, P04775, P08104, P15389, P15390, P35498, P35499, Q14524, Q15858, Q62205, Q62968, Q6QIY3, Q99250, Q9ER60, Q9JJV9, Q9NY46, Q9R053, Q9UI33, Q9UQD0, Q9WTU3, Q9Y5Y9
SCN10A, Scn11a, SCN1A, SCN2A, SCN3A, Scn4a, Scn5a, Scn8a, SCN9A
Synthesized peptide derived from the Internal region of human Na+ CP-pan.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.