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Invitrogen™ SP1 Recombinant Rabbit Monoclonal Antibody (HL1396)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547029

Catalog No. PIMA547029


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Description

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SP1
Recombinant Monoclonal
0.5 mg/mL
PBS with no preservative
O89090, P08047, Q01714
SP1
Recombinant protein encompassing a sequence within the center region of human SP1. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
HL1396
Unconjugated
SP1
1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Rabbit
Protein A
RUO
20683, 24790, 6667
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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