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SPIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7204319 Shop All Proteintech Group Inc Products
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50-172-7717 150 μL
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Catalog No. 50-172-7717 Supplier Proteintech Group Inc Supplier No. 121051AP150UL
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Description

Rabbit Polyclonal Antibody

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Specifications

Antigen SPIN1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SPIN1
Gene Accession No. Q4V8J7, Q61142, Q9Y657
Gene Alias OCR, Ovarian cancer related protein, SPIN, SPIN1, spindlin 1
Gene Symbols Spin1
Host Species Rabbit
Immunogen SPIN1 Fusion Protein Ag2750
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10927, 20729, 361217
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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