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SPTBN2/SCA5 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140656
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50-155-9301 20 μL
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Catalog No. 50-155-9301 Supplier Bethyl Laboratories, Inc Supplier No. A301117AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Spectrins are principle components of a cell′s membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]

Specifications

Antigen SPTBN2/SCA5
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SPTBN2
Gene Accession No. O15020
Gene Alias GTRAP41, SCA5
Gene Symbols SPTBN2
Host Species Rabbit
Immunogen Between 2340 and 2390
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6712
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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