SQSTM1/p62 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-2149	Rockland Immunochemicals 600401HB8	100 μg
50-199-2150	Rockland Immunochemicals 600401HB8S	25 μL

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human SQSTM1/p62. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to human, mouse, rat, and Pongo abelii. Cross reactivity with SQSTM1 from other sources has not been determined.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

• Antigen: SQSTM1/p62
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q13501, Q64337
• Gene ID (Entrez): 18412, 8878
• Primary or Secondary: Primary
• Product Type: Antibody

• Concentration: 1 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Alias: A170; BOS_7034; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; ORCA; OSF-6; Osi; OSIL; oxidative stress induced; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; Protein kinase C-zeta-interacting protein; sb:cb621; Sequestosome 1; Sequestosome-1; Sqstm1; STAP; STONE14; Ubiquitin-binding protein p62; zgc:85784; Zip; ZIP3
• Gene Symbols: Sqstm1
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: Sqstm1