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Tocris Bioscience™ SR 7826

Potent and selective LIMK inhibitor; antitumor

$322.48 - $1343.28

Specifications

Chemical Name or Material N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
CAS 1219728-20-7
Target LIMK Inhibitors
Molecular Formula C22H21N5O2
Formula Weight 387.43
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
562650
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Tocris Bioscience™
5626/50
50 mg
Each for $1,343.28
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562610
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Tocris Bioscience™
5626/10
10 mg
Each for $322.48
Add to Cart
 
Description

Description

Potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable.
Specifications

Specifications

N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
LIMK Inhibitors
387.43
1219728-20-7
C22H21N5O2
>98%
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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Documents

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