Invitrogen™ SRPX2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5106437	100 μL

Catalog No. PIPA5106437

Supplier: Invitrogen™ PA5106437

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SRPX2.

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

Specifications

• Antigen: SRPX2
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: SRPX2
• Gene Accession No.: B5DF94, O60687, Q8R054
• Gene Alias: 1110039C07Rik; BPP; CBPS; EMBL:AAI68975.1, ECO:0000312; PMGX; PubMed:24179158}; RESDX; RGD:1562444}; RGD1562444; RP11-524D16__A.1; SRP; SRPUL; SRPX2; srpx2 {ECO:0000312; sushi repeat containing protein X-linked 2; sushi repeat containing protein, X-linked 2; sushi repeat-containing protein SRPX2; sushi repeat-containing protein SRPX2 {ECO:0000303; sushi-repeat containing protein; sushi-repeat containing protein, X-linked 2; sushi-repeat protein; sushi-repeat protein upregulated in leukemia; sushi-repeat protein up-regulated in leukemia; sushi-repeat-containing protein, X-linked 2
• Gene Symbols: SRPX2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human SRPX2(Accession O60687), corresponding to amino acid residues G131-P181.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27286, 317181, 68792
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG