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SSB1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7141193
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50-156-1364 20 μL
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Catalog No. 50-156-1364 Supplier Bethyl Laboratories, Inc Supplier No. A301938AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for human tissues. Epitope retrieval with citrate buffer pH 6.0 is recommended for mouse tissues

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Specifications

Antigen SSB1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NABP2
Gene Accession No. Q8R2Y9, Q9BQ15
Gene Alias SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1, hSSB1, NABP2, OBFC2B, SSB1
Gene Symbols NABP2
Host Species Rabbit
Immunogen Between 161 and 211
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 69917, 79035
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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