ST3GAL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8526	150 μL

Catalog No. 50-172-8526 Supplier Proteintech Group Inc Supplier No. 131541AP150UL

Description

Rabbit Polyclonal Antibody

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determits of carbohydrate structures, such as the sialyl-Lewis X determits, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.

Specifications

• Antigen: ST3GAL6
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.19 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ST3GAL6
• Gene Accession No.: P61943, Q8VIB3, Q9Y274
• Gene Alias: Sialyltransferase 10, SIAT10, ST3Gal VI, ST3GAL6, ST3GALVI
• Gene Symbols: St3gal6
• Host Species: Rabbit
• Immunogen: ST3GAL6 Fusion Protein Ag3782
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10402, 304023, 54613
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG