ST3GAL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8526	Proteintech Group Inc 131541AP150UL	150 μL

Description

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determits of carbohydrate structures, such as the sialyl-Lewis X determits, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.

Specifications

• Antigen: ST3GAL6
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P61943, Q8VIB3, Q9Y274
• Gene ID (Entrez): 10402, 304023, 54613
• Immunogen: ST3GAL6 Fusion Protein Ag3782
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ST3GAL6

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Sialyltransferase 10, SIAT10, ST3Gal VI, ST3GAL6, ST3GALVI
• Gene Symbols: St3gal6
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody