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StAR Antibody (STAR/2154), Janelia Fluor™ 549, Novus Biologicals™
SDP

Catalog No. NB008765 Shop All R&D Systems Products
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NB008765 0.1 mL
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Catalog No. NB008765 Supplier Novus Biologicals Supplier No. NBP275742JF549
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Description

Mouse Monoclonal Antibody

StAR Monoclonal specifically detects StAR in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen StAR
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone STAR/2154
Conjugate Janelia Fluor 549
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Gene Symbols STAR
Host Species Mouse
Immunogen Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Test Specificity Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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