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STAT2 Polyclonal Antibody, Active Motif™
SDP

Catalog No. p-7188857
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50-199-3589 10 μL
50-199-3588 100 μL
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Catalog No. 50-199-3589 Supplier Active Motif Supplier No. 61652
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Description

Rabbit Polyclonal Antibody

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

Specifications

Antigen STAT2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Stat2
Gene Accession No. P52630
Gene Alias 1600010G07Rik; AW496480; BOS_5470; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT; STAT 2; STAT113; STAT2; STAT-2
Gene Symbols Stat2
Host Species Rabbit
Immunogen This antibody was raised against a peptide within the C-terminal region of human STAT2.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6773
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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