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Suz12 Polyclonal Antibody, Active Motif™
SDP

Catalog No. p-7188630
Encompass
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50-199-2691 10 μL
50-199-2692 50 μL
50-199-2690 100 μL
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Catalog No. 50-199-2691 Supplier Active Motif Supplier No. 39358
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Rabbit Polyclonal Antibody

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Specifications

Antigen Suz12
Applications ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene SUZ12
Gene Accession No. Q15022, Q80U70
Gene Alias 2610028O16Rik; AI195385; AU016842; AW536442; ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; KIAA0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit
Gene Symbols SUZ12
Host Species Rabbit
Immunogen This Suz12 antibody was raised against a peptide corresponding to the C-terminus of human Suz12.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23512, 52615
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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