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SYK Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140274
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Catalog No. Quantity
50-155-7922 20 μL
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Catalog No. 50-155-7922 Supplier Bethyl Laboratories, Inc Supplier No. A300559AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Pig

Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI). This trigges the phosphorylation of downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes. Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases. These kinases also help to activate Syk by phosphorylation of its activation loop.

Specifications

Antigen SYK
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SYK
Gene Accession No. P43405
Gene Alias Protein tyrosine kinase p72Syk
Gene Symbols SYK
Host Species Rabbit
Immunogen Between 350 and 400
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6850
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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