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TACE/ADAM17 Antibody - BSA Free, Novus Biologicals™
SDP

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Catalog No. NBP177044 Supplier Novus Biologicals Supplier No. NBP177044
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Description

Rabbit Polyclonal Antibody

TACE/ADAM17 Polyclonal specifically detects TACE/ADAM17 in Human, Rat samples. It is validated for Western Blot, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen TACE/ADAM17
Applications Western Blot, ELISA, Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.25-2 ug/mL, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 10 ug/ml
Formulation PBS with 0.02% Sodium Azide
Gene Accession No. NP_003174
Gene Alias ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM18, CD156B, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme
Gene Symbols ADAM17
Host Species Rabbit
Immunogen Antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TACE. The immunogen is located within the last 50 amino acids of TACE. Amino Acid Squence: ASFKLQRQNRVDSKETE
Molecular Weight of Antigen 93 kDa
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Apoptosis, Stem Cell Signaling Pathway
Primary or Secondary Primary
Gene ID (Entrez) 6868
Test Specificity 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated TACE/ADAM17. Human TACE/ADAM17 has 2 isoforms, including isoform A (824aa, 93kD), isoform B (694aa, 78.5kD). This antibody detects only isoform A. Mouse TACE/ADAM17 has 2 isoforms, long isoform (827aa, 93.1kD) and short isoform (655aa, 73.9kD). Rat TACE/ADAM17 has only one isoform identified so far (827aa, 93kD).
Target Species Human, Rat
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype IgG
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