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TADA3/TADA3L Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569756
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50-156-9756 10 μL
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Catalog No. 50-156-9756 Supplier Bethyl Laboratories, Inc Supplier No. A305186AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Orangutan

Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Specifications

Antigen TADA3/TADA3L
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene TADA3
Gene Accession No. O75528
Gene Alias ADA3, NGG1, TADA3L, hADA3, ADA3 homolog, ADA3-like protein, STAF54, transcriptional adapter 3
Gene Symbols TADA3
Host Species Rabbit
Immunogen Between 125 and 175
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10474
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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