Invitrogen™ TADA3L Polyclonal Antibody

Catalog No.	Quantity
PIPA527591	100 μL

Catalog No. PIPA527591

Supplier: Invitrogen™ PA527591

Description

Rabbit Polyclonal Antibody

Recommended positive controls: TADA3L tansfected 293T cell. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (90%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: TADA3L
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 9.46 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene: TADA3
• Gene Accession No.: O75528
• Gene Alias: 1110004B19Rik; ADA3; ADA3 homolog; ADA3-like protein; AI987856; alteration/deficiency in activation 3; fa03f04; FLJ20221; FLJ21329; hADA3; mADA3; NGG1; STAF54; Tada3; Tada3l; Transcriptional adapter 3; transcriptional adapter 3-like; transcriptional adaptor 3; transcriptional adaptor 3 (NGG1 homolog, yeast)-like; transcriptional adaptor 3-like isoform b; Unknown (protein for MGC:133915); wu:fa03f04; zgc:63596
• Gene Symbols: TADA3
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TADA3L. The exact sequence is proprietary.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10474
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG