TAG-72 Antibody (CC49), Alexa Fluor™ 350, Novus Biologicals™

Catalog No.	Quantity
NP233128A30	0.1 mL

Catalog No. NP233128A30 Supplier Novus Biologicals Supplier No. NBP233128AF350

Description

Mouse Monoclonal Antibody

TAG-72 Monoclonal specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TAG-72
• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: CC49
• Conjugate: Alexa Fluor 350
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
• Host Species: Mouse
• Immunogen: Purified TAG-72 protein
• Purification Method: Protein A or G purified
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
• Target Species: Human, Rat, Bovine, Canine
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ