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  5. Tocris Bioscience™ TAK 165

Tocris Bioscience™ TAK 165
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Catalog No. p-5546053
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Catalog No. Quantity
35-991-0R 10 mg
35-995-0R 50 mg
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Catalog No. 35-991-0R Supplier Tocris Bioscience™ Supplier No. 3599/10
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Description

Potent and selective ErbB2 inhibitor

TAK 165 is a potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo.

Specifications

Quantity 10 mg
Product Type TAK 165
Purity >99%
Molecular Weight (g/mol) 468.47
Inhibitors TAK 165

For Research Use Only

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