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Thermo Scientific™ Tango™ MLNR-bla U2OS Cells

Catalog No. K1862
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Catalog No. K1862 Supplier Thermo Scientific™ Supplier No. K1862
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Description

Tango™ MLNR-bla U2OS cells contain the human Motilin Receptor (MLNR) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Tango™ MLNR-bla U2OS cells contain the human Motilin Receptor (MLNR) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ MLNR-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Motilin.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_001507
Assay Entry Cell-based beta-arrestin recruitment
Cell State Dividing Cells
Content And Storage Tango™ MLNR-bla U2OS cells are shipped on dry ice, 8 x 106 cells/vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Cytoplasmic Tail Tail from AVPR2 GPCR
Detection Method Fluorescence
For Use With (Application) FRET
Human Protein Class G-Protein Coupled Receptor (GPCR)
Population Status Single Cell Clone Origin
Product Line Tango
Quantity 1 vial
Readout End Point
Target Entry MLNR
Cell Line U2OS
System Type Tango™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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