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Invitrogen™ TBX3 Polyclonal Antibody

Rabbit Polyclonal Antibody

$209.50 - $511.50

Specifications

Antigen TBX3
Concentration 500 μg/mL
Content And Storage -20°C
Applications Western Blot
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5119454
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Invitrogen™
PA5119454
200 μL
Each for $511.50
Only null left
Add to Cart
 
PIPA5121561
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Invitrogen™
PA5121561
20 μL
Each for $209.50
Only null left
Add to Cart
 
Description

Description

TBX3 Polyclonal Antibody for Western Blot

T-box 3 (TBX3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. The Tbx3 protein is a transcriptional repressor that binds the canonical Brachychury bindig sites, and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Tbx3 is required for normal mammary development and is also implicated in tumor development. Tbx3 expression also increases during osteoblast differentiation, and may function as a determinant of osteoblast cell numbers. Mutations in T-box 3 cause ulnar-mammary syndrome (MIM 181450), affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing results in three transcript variants encoding different isoforms; however, the nature of one full length variant has not been determined. Subsets of human breast cancer cell lines overexpress TBX36. in vitro, Tbx3 overexpression in mouse embryo fibroblasts leads to immortalization of cells. Truncated forms of Tbx3 are increased in plasma samples.
Specifications

Specifications

TBX3
-20°C
Polyclonal
Liquid
IgG
Human
Tbx3
bladder cancer related protein XHL; D5Ertd189e; T-box 3; T-box 3 (ulnar mammary syndrome); T-box protein 3; T-box transcription factor TBX3; TBX3; TBX3-ISO; UMS; XHL
Tbx3
Primary
Antigen affinity chromatography
500 μg/mL
Western Blot
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.05% ProClin 300
O15119
6926
Recombinant protein T-Box Protein 3. The antigen corresponds to amino acid range 107-220 of the target protein.
Antibody
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