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  5. Tocris Bioscience™ TC-I 15

Tocris Bioscience™ TC-I 15
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Catalog No. 452710
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45-271-0 10 mg
45-275-0 50 mg
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Catalog No. 45-271-0 Supplier Tocris Bioscience™ Supplier No. 4527/10
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Description

Potent α2β1 inhibitor; displays antithrombotic activity in vivo

TC-I 15 is a potent α2β1 integrin inhibitor (IC50 values for the inhibition of human platelet adhesion to type I collagen are 12 and 715 nM for platelets under static conditions and under flow, respectively). TC-I 15 displays selectivity for α2β1 over αvβ3, α5β1, α6β1 and αIIbβ3 at concentrations exceeding 1000 nM. TC-I 15 reduces collagen IV production in mesangial cells. Active in vivo; TC-I 15 prevents ferric chloride-induced clot formation in mice.

Chemical Identifiers

CAS 916734-43-5
Molecular Formula C23H28N4O6S2

Specifications

Quantity 10 mg
Formula Weight 520.62
Purity >98%
Molecular Weight (g/mol) 520.619
Chemical Name or Material TC-I 15

Safety and Handling

Recommended Storage Store at -20°C
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