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TC-I 15, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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916734-43-5
C23H28N4O6S2
520.619
XKLHCUGVLCGKKX-RBUKOAKNSA-N
tc-i 15,n-4r-5,5-dimethyl-3-phenylsulfonyl-4-thiazolidinyl carbonyl-3-phenylmethyl amino carbonyl amino-l-alanine
90488948
(2S)-2-[[(4R)-3-(benzenesulfonyl)-5,5-dimethyl-1,3-thiazolidine-4-carbonyl]amino]-3-(benzylcarbamoylamino)propanoic acid
CC1(C(N(CS1)S(=O)(=O)C2=CC=CC=C2)C(=O)NC(CNC(=O)NCC3=CC=CC=C3)C(=O)O)C
This item is not returnable. View return policy
916734-43-5
C23H28N4O6S2
520.619
XKLHCUGVLCGKKX-RBUKOAKNSA-N
tc-i 15,n-4r-5,5-dimethyl-3-phenylsulfonyl-4-thiazolidinyl carbonyl-3-phenylmethyl amino carbonyl amino-l-alanine
90488948
(2S)-2-[[(4R)-3-(benzenesulfonyl)-5,5-dimethyl-1,3-thiazolidine-4-carbonyl]amino]-3-(benzylcarbamoylamino)propanoic acid
CC1(C(N(CS1)S(=O)(=O)C2=CC=CC=C2)C(=O)NC(CNC(=O)NCC3=CC=CC=C3)C(=O)O)C

Potent α2β1 inhibitor; displays antithrombotic activity in vivo

Potent α2β1 integrin inhibitor (IC50 values for the inhibition of human platelet adhesion to type I collagen are 12 and 715 nM for platelets under static conditions and under flow, respectively). Displays selectivity for α2β1 over αvβ3, α5β1, α6β1 and αIIbβ3 at concentrations exceeding 1000 nM. Reduces collagen IV production in mesangial cells. Active in vivo; prevents ferric chloride-induced clot formation in mice.

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Quantity 10mg
Formula Weight 520.62
Percent Purity >98%
Chemical Name or Material TC-I 15

Recommended Storage : Store at -20°C