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Invitrogen™ TCAP Recombinant Rabbit Monoclonal Antibody (7E2Z4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA558055

Encompass_Preferred

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Catalog No. MA558055


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Description

Description

Immunogen sequence: MATSELSCEV SEENCERREA FWAEWKDLTL STRPEEGCSL HEEDTQRHET YHQQGQCQVL VQRSPWLMMR MGILGRGLQE YQLPYQRVLP LPIFTPAKMG ATKEEREDTP IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM SQEAQRG.

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TCAP
Recombinant Monoclonal
1.1 mg/mL
PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
O15273, O70548
Tcap
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1).
20 μL
Primary
Human, Mouse
Antibody
IgG
ELISA, Western Blot
7E2Z4
Unconjugated
Tcap
19 kDa sarcomeric protein; AI503981; AJ223855; CMD1N; CMH25; LGMD2G; limb girdle muscular dystrophy 2G (autosomal recessive); Tcap; T-cap; TELE; telethonin; teneurin C-terminal associated peptide; titin cap protein; titin-cap; titin-cap (telethonin)
Rabbit
Protein A
RUO
21393, 8557
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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