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Invitrogen™ TCAP Recombinant Rabbit Monoclonal Antibody (7E2Z4)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA558056

Description
Immunogen sequence: MATSELSCEV SEENCERREA FWAEWKDLTL STRPEEGCSL HEEDTQRHET YHQQGQCQVL VQRSPWLMMR MGILGRGLQE YQLPYQRVLP LPIFTPAKMG ATKEEREDTP IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM SQEAQRG.
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
Specifications
TCAP | |
Recombinant Monoclonal | |
1.1 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
O15273, O70548 | |
Tcap | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
ELISA, Western Blot | |
7E2Z4 | |
Unconjugated | |
Tcap | |
19 kDa sarcomeric protein; AI503981; AJ223855; CMD1N; CMH25; LGMD2G; limb girdle muscular dystrophy 2G (autosomal recessive); Tcap; T-cap; TELE; telethonin; teneurin C-terminal associated peptide; titin cap protein; titin-cap; titin-cap (telethonin) | |
Rabbit | |
Protein A | |
RUO | |
21393, 8557 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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