Selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor
Manufacturer: Tocris 5179/50
DescriptionSelective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor (IC50 = 0.6µM). Exhibits >100-fold selectivity for UCH-L3 over UCH-L1. Diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
- Chemical Name: 4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione
- Formula: C9H2Cl4O2
- CAS Number: 30675-13-9
- Solubility: Soluble to 50mM in DMSO
- Purity: >99
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