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TCS PIM-1 1, Tocris Bioscience™
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Catalog No. 297950
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Quantity:
10 mg
50 mg
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Description

Selective, ATP-competitive Pim-1 kinase inhibitor

ATP-competitive Pim-1 kinase inhibitor that displays selectivity over Pim-2 and MEK1/2 (IC50 values are 50, > 20000 and > 20000 nM for Pim-1, Pim-2 and MEK1/2 respectively).

Chemical Identifiers

CAS 491871-58-0
Molecular Formula C18H11BrN2O2
Molecular Weight (g/mol) 367.20
MDL Number MFCD00276275
InChI Key SVSYJTYGPLVUOZ-UHFFFAOYSA-N
Synonym tcs pim-1 1, 6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile, 3-cyano-4-phenyl-6-3-bromo-6-hydroxy phenyl-2 1h-pyridone, 6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1h-pyridine-3-carbonitrile, 2obj, pim1i, pyridone-based compound, 1, tcs pim-11, pim1-in-1 tcs pim-1 1, 3-cyano-4-phenyl-6-3-bromo-6-hydroxyphenyl-2-pyridone
PubChem CID 1235170
ChEBI CHEBI:86453
IUPAC Name 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
SMILES OC1=C(C=C(Br)C=C1)C1=CC(C2=CC=CC=C2)=C(C#N)C(=O)N1

Specifications

Quantity 50 mg
Formula Weight 367.2
Percent Purity >98%
Chemical Name or Material TCS PIM-1 1

Safety and Handling

Recommended Storage Store at +4°C
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