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Invitrogen™ TDP-43 Monoclonal Antibody (3H8)

Mouse Monoclonal Antibody

$526.00 - $1800.00

Specifications

Antigen TDP-43
Clone 3H8
Concentration 1 mg/mL
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIMA547322
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Invitrogen™
MA547322
500 μL
Each for $1,800.00
Only null left
Add to Cart
 
PIMA547420
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Invitrogen™
MA547420
100 μL
Each for $526.00
Only null left
Add to Cart
 
Description

Description

TDP-43 Monoclonal Antibody for Western Blot, ICC/IF, IHC (PFA)

TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
Specifications

Specifications

TDP-43
1 mg/mL
Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Unconjugated
Mouse
RUO
PBS with 50% glycerol and 5mM sodium azide
Q13148, Q921F2
100051482, 100739753, 230908, 23435, 298648, 540632
Full length recombinant human TDP43 expressed in and purified from E. coli.
Antibody
3H8
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Monoclonal
Liquid
IgG1 κ
Human, Mouse, Rat, Bovine, Pig, Horse
TARDBP
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
TARDBP
Primary
Protein A/G
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