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Invitrogen™ TDP-43 Monoclonal Antibody (3H8)
Mouse Monoclonal Antibody
$526.00 - $1800.00
Specifications
Antigen | TDP-43 |
---|---|
Clone | 3H8 |
Concentration | 1 mg/mL |
Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Applications | Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIMA547322
|
Invitrogen™
MA547322 |
500 μL |
Each for $1,800.00
|
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PIMA547420
|
Invitrogen™
MA547420 |
100 μL |
Each for $526.00
|
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Description
TDP-43 Monoclonal Antibody for Western Blot, ICC/IF, IHC (PFA)
TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.Specifications
TDP-43 | |
1 mg/mL | |
Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry | |
Unconjugated | |
Mouse | |
RUO | |
PBS with 50% glycerol and 5mM sodium azide | |
Q13148, Q921F2 | |
100051482, 100739753, 230908, 23435, 298648, 540632 | |
Full length recombinant human TDP43 expressed in and purified from E. coli. | |
Antibody |
3H8 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Monoclonal | |
Liquid | |
IgG1 κ | |
Human, Mouse, Rat, Bovine, Pig, Horse | |
TARDBP | |
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg | |
TARDBP | |
Primary | |
Protein A/G |
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