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TDP-43/TARDBP Antibody, Novus Biologicals™
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Catalog No. NBP229648 Shop All R&D Systems Products
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NBP229648 0.1 mL
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Catalog No. NBP229648 Supplier Novus Biologicals Supplier No. NBP229648
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Description

Rabbit Polyclonal Antibody

TDP-43/TARDBP Polyclonal specifically detects TDP-43/TARDBP in Human, Rat samples. It is validated for Western Blot, Immunohistochemistry.

Specifications

Antigen TDP-43/TARDBP
Applications Western Blot, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Dilution Western Blot 1:1000, Immunohistochemistry 1:250
Formulation PBS and 30% Glycerol with No Preservative
Gene Accession No. Q13148
Gene Alias ALS10TAR DNA-binding protein-43, TAR DNA binding protein, TDP43, TDP-43, TDP-43TAR DNA-binding protein 43
Gene Symbols TARDBP
Host Species Rabbit
Immunogen Synthetic peptide C-terminal to the caspase-cleavage site (between D219 and V220) of human TDP-43. Accession # Q13148. Accession # Q13148
Molecular Weight of Antigen 43 kDa
Purification Method Affinity purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Epigenetics, Immunology, microRNA, Mitochondrial Fusion Proteins, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Transcription Factors and Regulators, Virology Bacteria and Parasites
Primary or Secondary Primary
Gene ID (Entrez) 23435
Test Specificity Specific for the ∼ 43kDa TDP-43 protein in Western blots of rat brain lysate. Expected molecular weight is dependent upon the TDP-43 species present in sample (full-length vs. truncated TDP-43). Under non-denaturing conditions (for example, by IHC), this antibody detects TDP-43 inclusions in human brain tissue with TDP-43 proteinopathy, but does not detect full-length nuclear TDP-43. Under denaturing conditions (for example, by Western Blot analysis) this antibody detects the C-terminus of full-length and truncated human TDP-43.
Target Species Human, Rat
Content And Storage Store at -20C. Avoid freeze-thaw cycles.
Isotype IgG
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For Research Use Only

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