TDP-43/TARDBP Antibody, Novus Biologicals™

Rabbit Polyclonal Antibody

Supplier:  Novus Biologicals NBP229648

Catalog No. NBP229648

Description

TDP-43/TARDBP Polyclonal specifically detects TDP-43/TARDBP in Human, Rat samples. It is validated for Western Blot, Immunohistochemistry.

Specifications

• Antigen: TDP-43/TARDBP
• Classification: Polyclonal
• Dilution: Western Blot 1:1000, Immunohistochemistry 1:250
• Gene Accession No.: Q13148
• Gene Symbols: TARDBP
• Immunogen: Synthetic peptide C-terminal to the caspase-cleavage site (between D219 and V220) of human TDP-43. Accession # Q13148. Accession # Q13148
• Purification Method: Affinity purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Specific for the ∼ 43kDa TDP-43 protein in Western blots of rat brain lysate. Expected molecular weight is dependent upon the TDP-43 species present in sample (full-length vs. truncated TDP-43). Under non-denaturing conditions (for example, by IHC), this antibody detects TDP-43 inclusions in human brain tissue with TDP-43 proteinopathy, but does not detect full-length nuclear TDP-43. Under denaturing conditions (for example, by Western Blot analysis) this antibody detects the C-terminus of full-length and truncated human TDP-43.
• Content And Storage: Store at -20C. Avoid freeze-thaw cycles.

• Applications: Western Blot, Immunohistochemistry
• Conjugate: Unconjugated
• Formulation: PBS and 30% Glycerol with No Preservative
• Gene Alias: ALS10TAR DNA-binding protein-43, TAR DNA binding protein, TDP43, TDP-43, TDP-43TAR DNA-binding protein 43
• Host Species: Rabbit
• Molecular Weight of Antigen: 43 kDa
• Quantity: 0.1 mL
• Research Discipline: Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Epigenetics, Immunology, microRNA, Mitochondrial Fusion Proteins, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Transcription Factors and Regulators, Virology Bacteria and Parasites
• Gene ID (Entrez): 23435
• Target Species: Human, Rat
• Isotype: IgG

For Research Use Only