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Tenascin C Antibody (T2H5), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NB007531 Shop All R&D Systems Products
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NB007531 0.1 mL
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Catalog No. NB007531 Supplier Novus Biologicals Supplier No. NBP247919AF350
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Description

Mouse Monoclonal Antibody

Tenascin C Monoclonal specifically detects Tenascin C in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Tenascin C
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone T2H5
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias 150-225, Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion, hexabrachion (tenascin C, cytotactin), hexabrachion (tenascin), HXBcytotactin, JI, MGC167029, Myotendinous antigen, neuronectin, tenascin, tenascin C, Tenascin-C, tenascin-C isoform 14/AD1/16, TN-C, TNGP
Gene Symbols TNC
Host Species Mouse
Immunogen Human breast carcinoma (Uniprot: P24821)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer, Extracellular Matrix, Neuroscience, Prostate Cancer
Primary or Secondary Primary
Test Specificity In Western blotting, it reacts with two bands of ∼MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this monoclonal antibody is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Target Species Human, Rat (Negative)
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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