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Tenascin C Antibody (T2H5), Novus Biologicals™
SDP

Catalog No. NBP24458201 Shop All R&D Systems Products
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NBP24458201 0.1 mg
NBP24458200 0.02 mg
NBP24458202 0.2 mg
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Catalog No. NBP24458201 Supplier Novus Biologicals Supplier No. NBP2445820.1MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Tenascin C Monoclonal specifically detects Tenascin C in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Tenascin C
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone T2H5
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P24821
Gene Alias 150-225, Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion, hexabrachion (tenascin C, cytotactin), hexabrachion (tenascin), HXBcytotactin, JI, MGC167029, Myotendinous antigen, neuronectin, tenascin, tenascin C, Tenascin-C, tenascin-C isoform 14/AD1/16, TN-C, TNGP
Gene Symbols TNC
Host Species Mouse
Immunogen Human breast carcinoma
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer, Extracellular Matrix, Neuroscience, Prostate Cancer
Primary or Secondary Primary
Gene ID (Entrez) 3371
Test Specificity In Western blotting, it reacts with two bands of ∼MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Target Species Human, Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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